Buried deep within the dazzlingly intricate machinery of the human cell could lie a key to treating a range of deadly cancers, according to a team of scientists at Florida State University. In a new study, researchers discovered a critical missing step in the production of proteasomes—tiny structures in a cell that dispose of protein

Getting enough sleep is key to good health, and studies have shown that insufficient sleep increases the risk of serious problems, including cardiovascular disease. Now Massachusetts General Hospital (MGH) investigators have discovered one way that sleep protects against the buildup of arterial plaques called atherosclerosis. In their paper receiving advance online publication in Nature, they describe

Opioid-related deaths nationwide jumped fourfold in the last two decades, and the epidemic has made major inroads in the Eastern states, according to a new study by researchers at the Stanford University School of Medicine, Harvard University and the University of Toronto. “Although opioid-related mortality has been stereotyped as a rural, low-income phenomenon concentrated among Appalachian

A breakthrough test developed by Indiana University School of Medicine researchers to measure pain in patients could help stem the tide of the opioid crisis in Indiana, and throughout the rest of the nation. A study led by psychiatry professor Alexander Niculescu, MD, PhD and published this week in the Nature journal Molecular Psychiatrytracked hundreds of

A simple drug cocktail that converts cells neighboring damaged neurons into functional new neurons could potentially be used to treat stroke, Alzheimer’s disease, and brain injuries. A team of researchers at Penn State identified a set of four, or even three, molecules that could convert glial cells — which normally provide support and insulation for

The old adage “use it or lose it” tells us: if you stop using your muscles, they’ll shrink. Until recently, scientists thought this meant that nuclei—the cell control centers that build and maintain muscle fibers—are also lost to sloth. But according to a review published in Frontiers in Physiology, modern lab techniques now allow us

Prof. Rony Paz of the Weizmann Institute of Science suggests that our brains are like modern washing machines—evolved to have the latest sophisticated programming, but more vulnerable to breakdown and prone to develop costly disorders. He and a group of researchers recently conducted experiments comparing the efficiency of the neural code in non-human and human

The size of children’s heads is not only related to the growth of their skull, but also their brain. A genome-wide analysis, published in Nature Communications, now reports the largest known genetic effects on head circumference and the related measure of intracranial volume. Children’s heads expand steadily to accommodate their growing brains and doctors routinely

Scientists say they can predict whether a person can expect to live longer or die sooner than average, by looking at their DNA. The team has analysed the combined effect of genetic variations that influence lifespan to produce a scoring system. People who score in the top ten per cent of the population might expect

By combining deep learning algorithms and statistical methods, investigators from the Institute of Evolutionary Biology (IBE), the Centro Nacional de Análisis Genómico (CNAG-CRG) of the Centre for Genomic Regulation (CRG) and the Institute of Genomics at the University of Tartu have identified, in the genome of Asian individuals, the footprint of a new hominid who

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