Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don’t prevent infection or transmission via mosquitoes. What’s worse, the malaria parasite is developing resistance to existing drugs. “In many ways, the search for new malaria drugs has been a search

A major international collaboration headed by researchers from the Danish iPSYCH project, the Broad Institute of Harvard and MIT, Massachusetts General Hospital, SUNY Upstate Medical University, and the Psychiatric Genomics Consortium has for the first time identified genetic variants which increase the risk of ADHD. The new findings provide a completely new insight into the

Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million people in the United States. Some drug treatments can help alleviate the pain, but there are no treatments that can reverse or slow the cartilage breakdown associated with the disease. In an advance that could improve the treatment options available for osteoarthritis,

A major international collaboration headed by researchers from the Danish iPSYCH project, the Broad Institute of Harvard and MIT, Massachusetts General Hospital, SUNY Upstate Medical University, and the Psychiatric Genomics Consortium has for the first time identified genetic variants which increase the risk of ADHD. The new findings provide a completely new insight into the

Forget MRSA and E. coli, there’s another bacterium that is becoming increasingly dangerous due to antibiotic resistance — and it’s present on the skin of every person on the planet. A close relative of MRSA, Staphylococcus epidermidis, is a major cause of life-threatening infections after surgery, but it is often overlooked by clinicians and scientists

Brown University researchers have shown a way to use graphene oxide (GO) to add some backbone to hydrogel materials made from alginate, a natural material derived from seaweed that’s currently used in a variety of biomedical applications. In a paper published in the journal Carbon, the researchers describe a 3-D printing method for making intricate

One of the most important and surprising traits of the brain is its ability to reconfigure dynamically the connections to process and respond properly to stimuli. Researchers from Tohoku University (Sendai, Japan) and the University of Barcelona, using neuroengineering tools, have created in vitro neural circuits that reproduce the capacity of segregation and integration of

Which is better, a low-fat/high-carbohydrate diet or a high-fat/low-carbohydrate diet — or is it the type of fat that matters? In a new paper featured on the cover of Science magazine’s special issue on nutrition, researchers from Harvard T.H. Chan School of Public Health, Boston Children’s Hospital, and colleagues with diverse expertise and perspectives on the issues

Cancer scientists led by principal investigator Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have combined “liquid biopsy,” epigenetic alterations and machine learning to develop a blood test to detect and classify cancer at its earliest stages. The findings, published online today in Nature, describe not only a way to detect cancer, but hold

For the first time, researchers at the UNC School of Medicine showed they could target one brain region with a weak alternating current of electricity, enhance the naturally occurring brain rhythms of that region, and significantly decrease symptoms associated with chronic lower back pain. The results, published in the Journal of Pain and presented at

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