A large-scale genomic analysis has revealed some of the inner workings of the body clock, shedding new light on how it links to mental health and disease. The study, published in Nature Communications, suggests that being genetically programmed to rise early may lead to greater well-being and a lower risk of schizophrenia and depression. However, …
Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found. Non-steroidal anti-inflammatory drugs, or NSAIDs, improved the overall five-year survival rate from 25 percent to 78 percent for …
Research published today (Jan. 22) in the journal Brain reveals a new approach to Alzheimer’s disease (AD) that may eventually make it possible to reverse memory loss, a hallmark of the disease in its late stages. The team, led by University at Buffalo scientists, found that by focusing on gene changes caused by influences other …
Chemotherapy and radiation are effective cancer treatments because they kill rapidly dividing cells, including tumor cells. But for children—whose tiny bodies are still growing—these treatments can cause lifelong damage. This is particularly true for children with brain cancer, and researchers are working hard to find treatments that reduce side effects while remaining effective. Now, scientists …
Chaos in bodily regulation can optimize our immune system according to a recent discovery made by researchers at the University of Copenhagen’s Niels Bohr Institute. The discovery may prove to be of great significance for avoiding serious diseases such as cancer and diabetes. Wide gaps exist in our understanding of how the immune system works …
Fever is known to help power up our immune cells, and scientists in Shanghai have new evidence explaining how. They found in mice that fever alters surface proteins on immune cells like lymphocytes to make them better able to travel via blood vessels to reach the site of infection. Their work appears on January 15 …
The most deadly aspect of breast cancer is metastasis, cancer cells spreading throughout the body. Researchers at the University and the University Hospital of Basel have now discovered a substance that suppresses the formation of metastases. In the journal Cell, the team of molecular biologists, computational biologists and clinicians reports on their interdisciplinary approach. The …
Scientists have created the first retroviral CRISPR-Cas9 gene editing library to explore the regulation of mouse T cells, which are key cells in the immune system. Researchers from the Wellcome Sanger Institute and their collaborators have mapped the most important genes for controlling T helper cells, and identified several new regulatory genes. These could help …
A more comfortable and reliable blood-sugar monitoring system is being designed by researchers in Sweden for people with diabetes. After successfully testing a prototype of a microneedle patch on a human subject, the completion of a system for clinical tests is now underway. Continuous monitoring is a way to safely and reliably lower blood glucose …
Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer’s and even restores memories in mice, they report Jan. 2 in the journal Cell Reports. The binding of amyloid beta peptides to prion proteins triggers a cascade of devasting events in the progression of Alzheimer’s—accumulation of …
