A drug offers new hope in acute myeloid leukemia. Credit: © designer491 / Fotolia A new drug shows promise in its ability to target one of the most common and sinister mutations of acute myeloid leukemia (AML), according to researchers at the Perelman School of Medicine at the University of Pennsylvania and Penn’s Abramson Cancer

This is the first study to make a direct connection between birth outcomes and placental oxygen transport. Credit: © beeboys / Fotolia When a baby is born small, it’s often attributed to genetic factors or maternal risk factors like poor nutrition or smoking. But a twin study led by researchers at Boston Children’s Hospital now

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome. Credit: Christ-claude Mowandza-ndinga (UNC Health Care) Scientists have known for decades that smoking cigarettes

Scientists have documented reversal of advanced type 1 diabetes in mice and subsequently completed a successful phase I human clinical trial of BCG vaccination. Credit: © designer491 / Fotolia Interim results from a FDA-approved clinical trial testing the generic vaccine bacillus Calmette-Guérin (BCG) to reverse advanced type 1 diabetes are being presented at the 75th

Dr. Franck Mauvais-Jarvis, a leading voice in the debate to bring sex parity to pre-clinical research, is a professor of endocrinology at Tulane University School of Medicine. Credit: Paula Burch-Celentano/Tulane University Over the last decade, many drugs that have been pulled from the market due to toxicity were withdrawn because they affected women more than

More than 100 million Americans suffer from chronic pain and this figure is expected to grow, driven by the increased life expectancy, increasing incidence of diabetes and cancer, combined with better survival rates, often leaving patients with severe and poorly treated pain. Credit: © Michail Petrov / Fotolia Researchers from Monash University have developed a

This is a cross-section of tooth showing laser removal of the dentine layer, in tan, for analysis of metal content. Credit: J. Gregory, Copyright Mount Sinai Health System, 2017 Using evidence found in baby teeth, researchers from The Senator Frank R. Lautenberg Environmental Health Sciences Laboratory and The Seaver Autism Center for Research and Treatment

There are epigenetic changes in women consuming tea, but not in men, shows new research. Credit: © Ivan Kruk / Fotolia Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consumption in women leads to epigenetic changes in genes that are

How Vmem signal strengthens innate immune response: Normal tadpoles have polarized cells, with specific native amounts and distributions of melanocytes (pigment cells) and primitive myeloid cells (part of the innate immune system). Following chemical or genetic treatments that depolarize the cells’ Vmem (transmembrane potential, or voltage potential caused by differences in negative and positive ions

This is a GIF depicting how a subgroup of neurons in the zona incerta influence binge-eating behavior in mice. Credit: Carla Schaffer / AAAS Researchers have identified a subgroup of neurons in the mouse brain that, upon activation, immediately prompt binge-like eating. Furthermore, repeated stimulation of these neurons over time caused the mice to gain

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